Bookshelf In a web-based survey that included more than 600 patients, 30.7% met the American College of Rheumatology criteria for a fibromyalgia diagnosis at a mean of 6 One anticytokine biologic, rituximab, depletes B cells which make antibodies. Fibromyalgia is a condition that can consist of pain and tenderness in the body. WebDue to your consent preferences, youre not able to view this. Bilge U, et al. Researchers say wearing green-tinted eyeglasses for several hours a day can help people with fibromyalgia reduce pain-related anxiety. Long COVID might include organ damage, depression, persistent loss of taste and smell, or any other new health issue that crops up in the wake of COVID-19. Is the ketogenic diet right for autoimmune conditions? Unable to load your collection due to an error, Unable to load your delegates due to an error. Because its more closely associated with viral triggers, ME/CFS has generated more attention from researchers than fibromyalgia. Fibromyalgia flare-ups are periods where fibromyalgia symptoms become worse than usual. Scientists use genetic rewiring to increase lifespan of cells, Beyond amyloid and tau: New targets in developing dementia treatments, Napping longer than 30 minutes linked to higher risk of obesity and high blood pressure, Activity 'snacks' could lower blood sugar, complication risk in type 1 diabetes, In Conversation: Investigating the power of music for dementia. (2021). Would you like email updates of new search results? Researchers have long suspected that these conditions are triggered by certain viruses. Are people with fibromyalgia at increased risk of COVID-19? [Systemic Mycoplasma blood infection in fibromyalgia and chronic fatigue syndrome]. Unable to load your collection due to an error, Unable to load your delegates due to an error. official website and that any information you provide is encrypted Just about any assault on the system of someone with fibromyalgia can lead to a flare. The condition is a known symptom of a COVID-19 infection. doi: 10.1371/journal.pone.0282385. Effect of COVID-19 pandemic lockdown on fibromyalgia symptoms. Moldofsky H, Patcai J. eCollection 2019. A 2021 study in The Lancet notes that it is advisable for those with rheumatic diseases to receive the COVID-19 vaccination. By Adrienne Dellwo An official website of the United States government. 8600 Rockville Pike The current review summarizes the available data linking fibromyalgia to either infection or vaccination. "I was not myself, meaning I didn't feel well for about 10 months.". Bethesda, MD 20894, Web Policies Fibromyalgia often makes 73-year-old Nancy Ries feel invisible. Also, a 2015 study found that fibromyalgia symptoms didnt change after participants received the flu vaccine, which has similar side effects to the COVID-19 vaccine. Cureus is on a mission to change the long-standing paradigm of medical publishing, where submitting research can be costly, complex and time-consuming. The site is secure. They are called long-haulers because they deal with symptoms for the long haul. What if you had a condition where medications and vaccines have the potential to trigger long periods of debilitation? doi: 10.1371/journal.pone.0261772. The reports from people three months after coming down with a suspected coronavirus infection (n=131) were not encouraging. Would you like email updates of new search results? Can diet help improve depression symptoms? 2020;382:1708-20. Unauthorized use of these marks is strictly prohibited. The most common side effects in those with arthritis include: The side effects are usually short-term and will resolve without treatment. official website and that any information you provide is encrypted A web-based survey published in 2021 found that 31% of people with "long COVID" reported symptoms that meet the diagnostic criteria for fibromyalgia six months after having COVID-19. Epub 2021 May 18. It also looks at how safe and effective the vaccine is for those with arthritis. La informacin contenida en el sitio web de CreakyJoints Espaol se proporciona nicamente con fines de informacin general. However, some people do experience a flare after getting a vaccine. Acupuncture for Fibromyalgia: Does It Work to Relieve Symptoms and Pain? Clinical characteristics of coronavirus disease 2019 in China. For most people, however, the side effects are temporary. Psychol Health. Studies have shown that people with fibromyalgia are struggling with anxiety and access to support systems and treatments due to COVID restrictions. There is no evidence to date that the vaccine triggers flare-ups in osteoarthritis. Although information pertaining to the risk of autoimmune disease as a consequence of vaccination is controversial, we merely propose our current understanding of autoimmune manifestations associated with COVID-19 vaccine. National Library of Medicine The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). "If I had to do it all over again, I would do the same thing because we have to be protected," she said. There is a need to determine distinctions between the FMS clinical status that emerged following COVID-19 and the regular patient group in terms of diagnosis, treatment, and follow-up. "The second shot was awful," she said. (2020). Dr. Volkmann says the first two shots are designed to be close together to produce an immune response. 2020;324(6):603-605. doi:10.1001/jama.2020.12603. Online ahead of print. WebDue to your consent preferences, youre not able to view this. Healthcare providers recommend exercise, relaxation techniques, and finding a way to connect with loved ones and a social network to manage anxiety, ease chronic pain, and overcome fatigue. HHS Vulnerability Disclosure, Help CreakyJoints no brinda consejos mdicos ni se dedica a la prctica de la medicina. Remain stocked up on basics (like toilet paper) and other commodities you need. Hum Cell. Before The https:// ensures that you are connecting to the The Centers for Disease Control and Prevention (CDC) recommends that everyone age 5 and older receive a COVID-19 vaccine. Indeed, it is the only thing that ever has.". The pathogenesis of fibromyalgia is not completely understood. It can cause fatigue and cognitive issues, such as difficulty thinking. This means that most people with arthritis do not need to avoid any particular COVID-19 vaccine. The condition is a known symptom of a COVID-19 infection. The effect of novel coronavirus disease 2019 (COVID-19) on fibromyalgia syndrome [Abstract]. As with the symptoms of acute disease, these long-haul symptoms are strikingly similar to fibromyalgia and its close cousin, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). 2011 Nov-Dec;29(6 Suppl 69):S118-26. Fibromyalgia affects around 5% of the world's population. The .gov means its official. However, a person should contact a doctor if the side effects persist or steadily worsen. The chronic disorder, which can cause pain, fatigue and sleep loss makes Nancy think twice about everything, including the COVID-19 vaccines. August 31, 2021. https://www.medpagetoday.com/rheumatology/fibromyalgia/94299. These reports could help guide clinical assessment and management of autoimmune manifestations after COVID-19 vaccination. Results from a web-based survey" RMD Open 2021; doi:10.1136/rmdopen-2021-001735. August 31, 2021. (2018). Unauthorized use of these marks is strictly prohibited. Lee YH, Kim JH, Song GG (2015) Association between the COMT Val158Met polymorphism and fibromyalgia susceptibility and fibromyalgia impact questionnaire score: a meta-analysis. Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. eCollection 2023. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. COVID-19 and immunosuppression: A review of current clinical experiences and implications for ophthalmology patients taking immunosuppressive drugs. The key issue for people with fibromyalgia is identifying the difference between fibromyalgia symptoms and virus symptoms because the two can overlap. However, with how closely theyre related and how similar the symptoms are, its possible that both conditions will see an upswing in diagnoses in the near future. Tseng HF, et al. The Author(s), under exclusive licence to International League of Associations for Rheumatology (ILAR). Centers for Disease Control and Prevention (CDC). PMC 2021 Fall;32(3):219-221. doi: 10.5080/u26175. The cases of Lyme disease, mycoplasma, hepatits C and HIV are detailed. Pope JE. (2021). Terakawa K, Niikura T, Katagiri D, Sugita A, Kikuchi T, Hayashi A, Suzuki M, Takano H. CEN Case Rep. 2023 Apr 27:1-7. doi: 10.1007/s13730-023-00792-9. Fibromyalgia: Pathogenesis, mechanisms, diagnosis, and treatment options update. Additionally, the Centers for Disease Control and Prevention (CDC) provide a vaccine finder. WebWe found that 57% of patients with pSS affected by COVID-19 remain symptomatic after a mean follow-up of 5 months. COVID Long Haulers: Long-Term Effects of COVID-19. As new research becomes available, well update this article. 2023 Apr 13;18(4):e0282385. Schovsbo SU, Mllehave LT, Petersen MW, Ahrendt Bjerregaard A, Eliasen M, Pedersen SB, Eplov LF, Krhus LL, Fink P, Linneberg A, Dantoft TM, Jrgensen T, Benros ME. The contents of this website are for informational purposes only and do not constitute medical advice.CreakyJoints.org is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Against COVID-19 Post-Acute Care Study Group. A 2021 study involving 1,519 people with arthritis and other musculoskeletal conditions found that only 5 in 100 of the participants experienced flare-ups following the COVID-19 vaccine, and only 1.2% experienced severe flare-ups. By joining Cureus, you agree to our One 2022 study tracked 78 people with fibromyalgia before and during the pandemic and found "significant fibromyalgia symptom deterioration" including increases in pain, anxiety, and depression. CreakyJoints is a digital community for millions of arthritis patients and caregivers worldwide who seek education, support, advocacy, and patient-centered research. However, many people with fibromyalgia have other health conditions (comorbidities) that do raise the risk for severe COVID-19. FMS-related symptoms occur in a subset of individuals following COVID-19. It is important to note that COVID-19 vaccines are free for everyone, including those without health insurance. Vincent A, et al. Please enable it to take advantage of the complete set of features! It often affects one joint at a time, most commonly your big toes. As such, the COVID-19 vaccine may have the added benefit of helping prevent a worsening of the fibromyalgia symptoms that you may already cope with daily. Among the probable mechanisms are alterations in inflammatory and anti-inflammatory pathways. A person should consult a doctor about the risks and benefits of continuing medications. This includes people with arthritis. Unauthorized use of these marks is strictly prohibited. However, they did not find a significant increased risk of fibromyalgia among those who had been hospitalized with COVID. There are currently no reports in the scientific or medical literature of fibromyalgia flare-ups following the COVID-19 vaccine. We represent patients through our popular social media channels, our website CreakyJoints.org, and the 50-State Network, which includes nearly 1,500 trained volunteer patient, caregiver and healthcare activists. Possible mechanistic links between fibromyalgia and HIV are reviewed. Accessibility Apractical approach for the treatment of post-COVID symptoms. 2019;20(20):5164. doi:10.3390/ijms20205164. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine. Federal government websites often end in .gov or .mil. Bethesda, MD 20894, Web Policies There is evidence that neuroinflammatory pathways affect neuroplasticity in the central nervous system and trigger the onset of FMS-related symptoms. They may also want to undergo testing to ensure their bodies have produced antibodies in response to the vaccine. Should people with arthritis get a vaccine? What is RA? Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems networkUnited States, March-June 2020. Some people who get sick with COVID-19 experience symptoms that linger for months afterward. RMD Open. Persistent symptoms in patients after acute COVID-19. Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Johns Hopkins Medicine. 2021 Jul;121:102663. doi: 10.1016/j.jaut.2021.102663. government site. Opens in a new tab or window, Visit us on LinkedIn. Effectiveness of mRNA-1273 against SARS-CoV-2 Omicron and Delta variants [Abstract]. Walsh N. Fibromyalgia: A New Feature of Long COVID? The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. There arent any specific COVID-19 vaccine guidelines for people with fibromyalgia. Yanmaz MN, Mert M, Korkmaz M. The prevalence of fibromyalgia syndrome in a group of patients with diabetes mellitus. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. We will be providing updated information, community support, and other resources tailored specifically to your health and safety. WebFibromyalgia can feel similar to osteoarthritis, bursitis, and tendinitis. Results from a web-based survey. It also helps prevent people from developing a severe illness with COVID-19 if they contract the virus. In a web-based survey that included more than 600 patients, 30.7% met the American College of Rheumatology criteria for a fibromyalgia diagnosis at a mean of 6 months after having had COVID-19, said Francesco Ursini, MD, PhD, of the University of Bologna, and colleagues. FOIA COVID-19 associated hospitalization in 571 patients with fibromyalgia a population-based study. 2023 Feb 14;116(1):26-39. doi: 10.1093/qjmed/hcac185. "Patients with fibromyalgia and chronic fatigue syndrome represent a vulnerable patient population as it relates to vaccines," said Dr. Elizabeth Volkmann. Fibromyalgia is a chronic condition that causes widespread pain throughout the body's muscles and other soft tissues. doi:10.5455/JPMA.32. The current definition of fibromyalgia requires a score of 13 or higher on the Fibromyalgia Symptom Scale, which combines scores on the Widespread Pain Index and Symptom Severity Scale. J Autoimmun 27:145152. COVID-19; Fibromyalgia syndrome; Post-COVID-19 syndrome. LOS ANGELES (KABC) -- What if you had a condition where medications and vaccines have the potential to trigger long periods of debilitation? Fibromyalgia affects around 5% of the world's population. This doesnt mean that you should stop taking your medications. To find out whether post-COVID syndrome was actually causing some people to develop fibromyalgia (including the chronic pain that goes along with it), Italian researchers decided to perform a web-based study. government site. 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Some COVID symptoms are not associated with fibromyalgia, including chills, congestion or a runny nose, cough, fever, and sore throat. The need for COVID-19 vaccines has created quite a dilemma for these patients. In addition, viral triggers have been linked with the development of fibromyalgia. Collie S, et al. They should go away within a few days. "In light of the overwhelming numbers of the SARS-CoV-2 pandemic, it is reasonable to forecast that rheumatologists will face a sharp rise in cases of a new entity that we defined as 'FibroCOVID,'" the researchers wrote online in RMD Open: Rheumatic & Musculoskeletal Diseases. Discover symptoms such as fibro fog, restless legs, and more. Turk Psikiyatri Derg. The symptoms of fibromyalgia and of chronic fatigue syndrome are very similar, if not superimposable to some forms of long Covid Syndrome. reumatismo.org/index.php/reuma/article/view/823, journals.plos.org/plosone/article?id=10.1371/journal.pone.0261772, jpma.org.pk/article-details/8683?article_id=8683, cdc.gov/media/releases/2022/s0519-covid-booster-acip.html, sciencedirect.com/science/article/abs/pii/S0049017221000275, cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html, cdc.gov/coronavirus/2019-ncov/vaccines/expect/after.html, arthritis.org/health-wellness/about-arthritis/related-conditions/other-diseases/fibro-patient-experience-with-covid-19-vaccine, clinexprheumatol.org/abstract.asp?a=16454, ncbi.nlm.nih.gov/pmc/articles/PMC8068842/, cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html, cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html, academic.oup.com/painmedicine/article/17/3/463/1888231, Everything You Need to Know About Fibromyalgia, 60% of Americans Have an Underlying Condition That Increases COVID-19 Risk, Your COVID-19 Vaccine Is Still Working Even If You Dont Have Side Effects. In contrast, hypertension was significantly higher among fibromyalgia patients (27% vs 10.8%, P<0.0001), as was mean body mass index (30.4 vs 23, P<0.0001) and the prevalence of obesity (49.2% vs 2.1%, P<0.0001). Fibromyalgia is poorly understood. 2023 Mar 25;12(2):100-108. doi: 10.5501/wjv.v12.i2.100. If you think anxiety is taking a toll on you, talk to your healthcare provider about how you may be able to manage it better. Both PCR and antigen tests can detect current infections. Med Hypotheses. Other fibro 2013;110:303-314. doi:10.1016/B978-0-444-52901-5.00025-3. Among the survey respondents who had fibromyalgia, 57% were women, a percentage that was lower than the 77.4% of women in the cohort overall, suggesting that men more often developed the musculoskeletal sequelae, the researchers explained. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); CreakyJoints is a digital community for millions of arthritis patients and caregivers worldwide who seek education, support, advocacy, and patient-centered research. The lowest antibody response was among those taking Janus kinase (JAK) inhibitors. Before National Library of Medicine Due to this, people do not receive this until after vaccination is complete. Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study. If it's positive, isolate and contact a provider or pharmacy for treatment options. Autoimmun Rev. If you have fibromyalgia, getting vaccinated, and staying up to date with booster shots, is the best way to protect yourself. MMWR Morb Mortal Wkly Rep. 2020;69:382386. Similarly, severe acute respiratory syndrome (SARS), which is also caused by a coronavirus, led to long-term post-viral illness that, according to a 2011 study, overlaps with the clinical and sleep features of [fibromyalgia] and chronic fatigue syndrome.. 2022. MNT is the registered trade mark of Healthline Media. Signs and Treatments for Anxiety in Fibromyalgia. WebFibromyalgia, infection and vaccination: two more parts in the etiological puzzle As the pathogenesis of fibromyalgia continues to raise debate, multiple putative triggers have Thus far, it's not classified as an autoimmune disease, where your immune system attacks healthy cells by mistake, although evidence suggests that it may have an autoimmune component. 90.5% of this population were females and 38.1% were within the 50-59 years age group. Aloush V, Gurfinkel A, Shachar N, Ablin JN, Elkana O. Original research: Fibromyalgia: a new facet of the post-COVID-19 syndrome spectrum? Cheng JC, Anzolin A, Berry M, Honari H, Paschali M, Lazaridou A, Lee J, Ellingsen DM, Loggia ML, Grahl A, Lindquist MA, Edwards RR, Napadow V (2022) Dynamic functional brain connectivity underlying temporal summation of pain in fibromyalgia. WebCOVID-19 and fibromyalgia have a few symptoms in common, like: Tiredness Pain Body aches Headache Diarrhea These shared symptoms may make it hard to know if you None of the COVID-19 vaccines available in the U.S. contains live viruses. 2021 Dec 30;16(12):e0261772. Symptoms of fibromyalgia may include: pain throughout the body, particularly in the back or neck. If you have any vaccine-related questions or concerns, be sure to discuss them with a doctor. How would I even know if I have COVID?. Heitmann J, Kreutz J, Aldudak S, Schieffer E, Schieffer B, Schfer AC. Medpage Today is among the federally registered trademarks of MedPage Today, LLC and may not be used by third parties without explicit permission. If you arent being treated with immunosuppressants, your fibromyalgia shouldnt put you at high risk for catching COVID-19. Developing COVID-19 may cause the symptoms of fibromyalgia to worsen. Ryabkova VA, Churilov LP, Shoenfeld Y. Neuroimmunology: What role for autoimmunity, neuroinflammation, and small fiber neuropathy in fibromyalgia, chronic fatigue syndrome, and adverse events after human papillomavirus vaccination?. My autoimmune disease makes the COVID vaccine not totally risk-free. Among the symptoms reported during the acute viral illness were anosmia/ageusia in 70.9%, myalgia in 70.4%, fever in 67.7%, and arthralgia in 64.6%. New-Onset Acute Kidney Disease Post COVID-19 Vaccination. Medication and other stress-management techniques like yoga and meditation may help you get your anxiety under control with fewer symptom flares. 2022 Nov 2;12(11):e066037. Its estimated that fibromyalgia impacts about 5 percent of the worlds population. Symptoms often begin after an event, such as Like all other individuals, fibromyalgia syndrome (FMS) patients were affected by these conditions. As always, it pays to be prepared for a flare: Anxiety is a common symptom in fibromyalgia and one that can be crippling at times. The Centers for Disease Control and Prevention (CDC) tracked underlying health conditions in people diagnosed with COVID-19 from February through March of 2020. WebFMS-related symptoms occur in a subset of individuals following COVID-19. Fortunately, COVID-19 vaccines are safe and effective for people with fibromyalgia. Online ahead of print. Study participants completed surveys that asked about the severity of their COVID infection as well as symptoms that might pertain to fibromyalgia. (2015). Letter to the Editor: THE IMPACT OF THE COVID-19 PANDEMIC ON SCHIZOPHRENIA PATIENTS. This trend appears to be continuing: Fibromyalgia has not emerged as one of the conditions healthcare providers and hospitals are seeing in a lot of people theyre treating for COVID-19. Subscribe to CreakyJoints for more related content. Additionally, receiving the COVID-19 vaccine may be of particular benefit to people with arthritis, especially those with RA, who are at greater risk of contracting SARS-CoV-2 and experiencing severe illness due to COVID-19. Despite this, most data show that the COVID-19 vaccine is safe for people with arthritis. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Alzheimers Res Ther. This is because mRNA vaccines are more effective and have a better overall safety profile than the J&J vaccine. The COVID-19 vaccine is safe and effective for people with fibromyalgia. Fibromyalgia is a chronic condition that causes widespread pain throughout the body's muscles and other soft tissues. Nancy Walsh, Contributing Writer, MedPage Today "We typically find that that second dose that was given three to four weeks later, is the one that really does it in terms of causing more inflammation," Volkmann said. Each state has its own COVID-19 vaccine policies and procedures. Now a new study confirms that similar symptoms often arise in people with post-COVID syndrome. government site. If people are concerned about receiving the COVID-19 vaccine, they should consult a healthcare professional. The study found that most adverse effects were the same as those experienced by the general population. Emotional stress can also lead to a flare-up. The relationship between COVID-19 and fibromyalgia syndrome: prevalence, pandemic effects, symptom mechanisms, and COVID-19 vaccines. Common etiology of posttraumatic stress disorder, fibromyalgia, chronic fatigue syndrome and multiple chemical sensitivity via elevated nitric oxide/peroxynitrite. Aug. 4 (UPI) -- The COVID-19 vaccine rarely causes disease flares in people with rheumatoid arthritis and lupus, according to a study published Wednesday by the (2022). Burns J, Movsisyan A, Stratil JM, Coenen M, Emmert-Fees KM, Geffert K, Hoffmann S, Horstick O, Laxy M, Pfadenhauer LM, von Philipsborn P, Sell K, Voss S, Rehfuess E. Cochrane Database Syst Rev. 2001 Aug;57(2):139-45. doi: 10.1054/mehy.2001.1325. Coping with fibromyalgia during the COVID-19 pandemic: adjustment and wellbeing. Changes in the autonomic nervous system with the effect of SARS-CoV-2 may induce the emergence of FMS-related symptoms. National Library of Medicine Results from a web-based survey. That's what happened to Nancy. Salaffi F, et al. (2022). immune thrombotic thrombocytopenia, autoimmune liver We avoid using tertiary references. Fibromyalgia is not on the list of pre-existing conditions that appear to make COVID-19 more severe. All rights reserved. The lack of answers made her feel even more invisible. The article looks at the types, causes, and treatments, including natural. Qasim H, Rahhal A, Husain A, Alammora A, Alsa'ed K, Alsayed AAM, Faiyoumi B, Maen AbuAfifeh L, Abu-Tineh M, Alshurafa A, Yassin MA. Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine. However, if a person has a high risk of blood clots, a doctor may have a vaccine preference for them. Results from a web-based survey - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means its official. By contrast, 42 (16.9%) patients who received the 2nd dose of the vaccine had flare symptoms. Fibromyalgia affects around 5% of the world's population. Bookshelf U.S. Centers for Disease Control and Prevention. Immune-mediated liver injury following COVID-19 vaccination. 2023 Healthline Media LLC. Fibromyalgia flares: A qualitative analysis. Fibromyalgia is a chronic condition that causes widespread pain throughout the body's muscles and other soft tissues. 2023 Feb 7. A person can try visiting the state department of health for help finding a vaccine locally. WebThere are two types of vaccines. Fibromyalgia does not appear to be a risk factor for severe COVID-19. Driver rescued after car plunges more than 500 feet off NorCal cliff, Authorities continue search for Texas man suspected of killing 5, Lakers, LeBron James to play Warriors, Steph Curry in NBA showdown. (2021). Studies show that a small percentage of people may experience a flare-up of eczema symptoms after receiving the COVID-19 vaccine, but the symptoms are easily Dasgupta A, Kalhan A, Kalra S.Long term complications and rehabilitation of COVID-19 patients. The chronic Molecular mimicry, the production of particular autoantibodies and the role of certain vaccine adjuvants seem to be substantial contributors to autoimmune phenomena.
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